CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023350
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Acidic leucine-rich nuclear phosphoprotein 32 family member A 
Protein Synonyms/Alias
  
Gene Name
 Anp32a 
Gene Synonyms/Alias
 Mapmodulin; CG5784 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
102IKDLETLKPLEEFKNacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex (By similarity). 
Sequence Annotation
 REPEAT 16 37 LRR 1.
 REPEAT 39 60 LRR 2.
 REPEAT 61 83 LRR 3.
 REPEAT 84 105 LRR 4.
 DOMAIN 118 156 LRRCT.  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Leucine-rich repeat; Nucleus; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 261 AA 
Protein Sequence
MEKRIELERR ARKVNQITEL NLDNCRSTSI VGLTDEYTAL ESLSLINVGL TTLKGFPKLP 60
NLKKLELSDN RISSGLNYLT TSPKLQYLNL SGNKIKDLET LKPLEEFKNL VVLDLFNNDA 120
TQVDNYREKI FKMLPSLNFL DGFDCNDEEV QSDGDDDDEV NGNDSDEVGV SDEDDDSDDS 180
DEEANGEVSL SEVYNDDLEE DNSDWEGEDE AGEEDEEEDS DIDDADGDAN ESAASVNAKD 240
KDGEKEADES QVRGKKRKHD G 261 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.
 GO:0005875; C:microtubule associated complex; ISS:FlyBase.
 GO:0005634; C:nucleus; ISS:UniProtKB.
 GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
 GO:0008017; F:microtubule binding; ISS:FlyBase.
 GO:0007017; P:microtubule-based process; ISS:FlyBase.
 GO:0006913; P:nucleocytoplasmic transport; ISS:UniProtKB. 
Interpro
 IPR001611; Leu-rich_rpt.
 IPR025875; Leu-rich_rpt_4.
 IPR003603; U2A'_phosphoprotein32A_C. 
Pfam
 PF12799; LRR_4 
SMART
 SM00446; LRRcap 
PROSITE
 PS51450; LRR 
PRINTS