CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034977
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Mut 
Protein Synonyms/Alias
 RCG43751 
Gene Name
 Mut 
Gene Synonyms/Alias
 LOC100361295; rCG_43751 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
52AKKQLKGKNPEDLIWacetylation[1]
87PEELPGVKPFTRGPYacetylation[1]
210EQGVPKEKLTGTIQNacetylation[1]
333LWAHLIEKMFQPKNSacetylation[1]
338IEKMFQPKNSKSLLLacetylation[1]
341MFQPKNSKSLLLRAHacetylation[1]
604SAIKRVNKFMEREGRacetylation[1]
619RPRLLVAKMGQDGHDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 748 AA 
Protein Sequence
MLRAKNQLFL LSPHYLKQLK DASSYRWKRL LHQQQPLHPE WAVLAKKQLK GKNPEDLIWH 60
TPEGISIKPL YSRADTMDLP EELPGVKPFT RGPYPTMYTY RPWTIRQYAG FSTVEESNKF 120
YKDNIKAGQQ GLSVAFDLAT HRGYDSDNPR VRGDVGMAGV AIDTVEDTKI LFDGIPLEKM 180
SVSMTMNGAV IPVLATFIVT GEEQGVPKEK LTGTIQNDIL KEFMVRNTYI FPPEPSMKII 240
ADIFQYTAQH MPKFNSISIS GYHMQEAGAD AILELAYTIA DGLEYCRTGL QAGLTIDEFA 300
PRLSFFWGIG MNFYMEIAKM RAGRRLWAHL IEKMFQPKNS KSLLLRAHCQ TSGWSLTEQD 360
PYNNIVRTAI EAMAAVFGGT QSLHTNSFDE ALGLPTVKSA RIARNTQIII QEESGIPKVA 420
DPWGGSYMME SLTNDVYEAA LKLIYEVEEM GGMAKAVAEG IPKLRIEECA ARRQARIDSG 480
SEVIVGVNKY QLEKEDSVEV LAIDNTSVRK KQIEKLKKIK SSRDQALAER SLNALTQCAA 540
SGDGNILALA VDAARARCTV GEITDALKKV FGEHKANDRM VSGAYRQEFG ESKEITSAIK 600
RVNKFMEREG RRPRLLVAKM GQDGHDRGAK VIATGFADLG FDVDIGPLFQ TPREVAQQAV 660
DADVHAVGVS TLAAGHKTLV PELIKELSAL GRPDILVMCG GVIPPQDYEF LYEVGVSNVF 720
GPGTRIPKAA VQVLDDIEKS LAEKQQSV 748 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0031419; F:cobalamin binding; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0004494; F:methylmalonyl-CoA mutase activity; IEA:Compara.
 GO:0072341; F:modified amino acid binding; IEA:Compara.
 GO:0050667; P:homocysteine metabolic process; IEA:Compara.
 GO:0009791; P:post-embryonic development; IEA:Compara. 
Interpro
 IPR006159; Acid_CoA_mut_C.
 IPR016176; Cbl-dep_enz_cat.
 IPR014348; Cbl-dep_enz_cat-sub.
 IPR006158; Cobalamin-bd.
 IPR006099; MeMalonylCoA_mutase_a/b_cat.
 IPR006098; MMCoA_mutase_a_cat. 
Pfam
 PF02310; B12-binding
 PF01642; MM_CoA_mutase 
SMART
  
PROSITE
 PS51332; B12_BINDING
 PS00544; METMALONYL_COA_MUTASE 
PRINTS