CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023006
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 PHD finger protein 11 
Protein Synonyms/Alias
 BRCA1 C-terminus-associated protein; Renal carcinoma antigen NY-REN-34 
Gene Name
 PHF11 
Gene Synonyms/Alias
 BCAP 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
99SFDVESVKKEIQRGRubiquitination[1]
100FDVESVKKEIQRGRKubiquitination[1]
125ATVGCDLKNCNKNYHubiquitination[1]
138YHFFCAKKDDAVPQSubiquitination[1]
217RHTDATVKVPFLKKCubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Positive regulator of Th1-type cytokine gene expression. 
Sequence Annotation
 ZN_FING 107 159 PHD-type; degenerate.  
Keyword
 Activator; Alternative splicing; Complete proteome; Metal-binding; Nucleus; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 331 AA 
Protein Sequence
MAQASPPRPE RVLGASSPEA RPAQEALLLP TGVFQVAEKM EKRTCALCPK DVEYNVLYFA 60
QSENIAAHEN CLLYSSGLVE CEDQDPLNPD RSFDVESVKK EIQRGRKLKC KFCHKRGATV 120
GCDLKNCNKN YHFFCAKKDD AVPQSDGVRG IYKLLCQQHA QFPIIAQSAK FSGVKRKRGR 180
KKPLSGNHVQ PPETMKCNTF IRQVKEEHGR HTDATVKVPF LKKCKEAGLL NYLLEEILDK 240
VHSIPEKLMD ETTSESDYEE IGSALFDCRL FEDTFVNFQA AIEKKIHASQ QRWQQLKEEI 300
ELLQDLKQTL CSFQENRDLM SSSTSISSLS Y 331 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001965; Znf_PHD.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
  
SMART
 SM00249; PHD 
PROSITE
 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2 
PRINTS