CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008663
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GTP-binding protein GTR2 
Protein Synonyms/Alias
  
Gene Name
 GTR2 
Gene Synonyms/Alias
 YGR163W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
259NSQKSSDKDNVINPRubiquitination[1]
334NARASQAKNSIEDDVubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 GTPase. Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome. Component of the EGO complex, a complex involved in the regulation of microautophagy. 
Sequence Annotation
 NP_BIND 16 23 GTP (Potential).
 NP_BIND 124 127 GTP (By similarity).  
Keyword
 3D-structure; Autophagy; Complete proteome; GTP-binding; Membrane; Nucleotide-binding; Protein transport; Reference proteome; Transport; Vacuole. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 341 AA 
Protein Sequence
MSLEATDSKA MVLLMGVRRC GKSSICKVVF HNMQPLDTLY LESTSNPSLE HFSTLIDLAV 60
MELPGQLNYF EPSYDSERLF KSVGALVYVI DSQDEYINAI TNLAMIIEYA YKVNPSINIE 120
VLIHKVDGLS EDFKVDAQRD IMQRTGEELL ELGLDGVQVS FYLTSIFDHS IYEAFSRIVQ 180
KLIPELSFLE NMLDNLIQHS KIEKAFLFDV NSKIYVSTDS NPVDIQMYEV CSEFIDVTID 240
LFDLYKAPVL RNSQKSSDKD NVINPRNELQ NVSQLANGVI IYLRQMIRGL ALVAIIRPNG 300
TDMESCLTVA DYNIDIFKKG LEDIWANARA SQAKNSIEDD V 341 
Gene Ontology
 GO:0034448; C:EGO complex; IDA:SGD.
 GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0031902; C:late endosome membrane; IDA:SGD.
 GO:0000790; C:nuclear chromatin; IDA:SGD.
 GO:0005525; F:GTP binding; ISA:SGD.
 GO:0016237; P:microautophagy; IMP:SGD.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR006762; Gtr1_RagA.
 IPR027417; P-loop_NTPase. 
Pfam
 PF04670; Gtr1_RagA 
SMART
  
PROSITE
  
PRINTS