CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026420
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Lymphocyte cytosolic protein 1 
Protein Synonyms/Alias
 Protein Lcp1 
Gene Name
 Lcp1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
82IKVFHGLKSTEVAKTacetylation[1]
88LKSTEVAKTFRKAINacetylation[1]
294TNFSTDIKDSKAYYHacetylation[1]
361DVVRGNPKLNLAFIAacetylation[1]
379NKYPALHKPENQDIDacetylation[1]
449VNRPPYPKLGGNMKKacetylation[1]
472DLGKNQAKFSLVGIAacetylation[1]
542SSSITSFKDPKISTSacetylation[1]
579ENLDDEEKLNNAKYAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; Calcium; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 627 AA 
Protein Sequence
MARGSVSDEE MMELREAFAK VDTDGNGYIS CNELNDLFKA ACLPLPGYRV REITENLMAT 60
GDLDQDGKIS FDEFIKVFHG LKSTEVAKTF RKAINKKEGI CAIGGTSEQS SVGTQHSYSE 120
EEKYAFVNWI NKALENDPDC RHVIPMNPNT DDLFNAVGDG IVLCKMVNLS VPDTIDERTI 180
NKKKLTPFTI QENLNLALNS ASAIGCHVVN IGAEDLKEGK PYLVLGLLWQ VIKIGLFADI 240
ELSRNEALIA LLREGESLED LMKLSPEELL LRWANYHLEN AGCTKITNFS TDIKDSKAYY 300
HLLEQVAPRG DEEGIPAVVI DMSGLREKDD IQRAECMLQQ AERLGCRQFV TATDVVRGNP 360
KLNLAFIANL FNKYPALHKP ENQDIDWGAL EGETREERTF RNWMNSLGVN PGVNHLYSDL 420
SDALVIFQLY EKIKVPVDWN RVNRPPYPKL GGNMKKLENC NYAVDLGKNQ AKFSLVGIAG 480
QDLNEGNRTL TLALVWQLMR RYTLNILEDI GGGQKVNDDI IVNWVNTTLK EAQKSSSITS 540
FKDPKISTSL PVLDLIDAIQ PGSINYDLLK TENLDDEEKL NNAKYAISMA RKIGARVYAL 600
PEDLVEVNPK MVMTVFACLM GKGMKRV 627 
Gene Ontology
 GO:0005884; C:actin filament; IEA:Compara.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0001891; C:phagocytic cup; IEA:Compara.
 GO:0001726; C:ruffle; IEA:Compara.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0051017; P:actin filament bundle assembly; IEA:Compara.
 GO:0031100; P:organ regeneration; IEP:RGD.
 GO:0033157; P:regulation of intracellular protein transport; IEA:Compara.
 GO:0002286; P:T cell activation involved in immune response; IEA:Compara. 
Interpro
 IPR001589; Actinin_actin-bd_CS.
 IPR001715; CH-domain.
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 
Pfam
 PF00307; CH
 PF13499; EF_hand_5 
SMART
 SM00033; CH
 SM00054; EFh 
PROSITE
 PS00019; ACTININ_1
 PS00020; ACTININ_2
 PS50021; CH
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS