UniProt Accession

 SSXT_HUMAN; Q15532; B0YJ95; Q16404; Q4VAX1; Q9BXC6 

Genbank Protein ID

 X79201; X79200; AF343880; EF445031; CH471088; BC096223; S79894 

Genbank Nucleotide ID

 CAA55792.1; AAK21314.1; ACA06073.1; EAX01210.1; AAH96223.1; AAB35674.1 

Protein Name

 Protein SSXT 

Protein Synonyms/Alias

 Protein SYT; Synovial sarcoma translocated to X chromosome protein 

Gene Name

 SS18 

Gene Synonyms/Alias

 SSXT; SYT 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
13	AAPRQRGKGEITPAA	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. 

Sequence Annotation

 REPEAT 344 356 1.
 REPEAT 357 369 2.
 REGION 1 186 Transcriptional activation.
 REGION 344 369 2 X 13 AA imperfect tandem repeats.
 MOTIF 50 53 SH2-binding (Potential).
 MOTIF 374 377 SH2-binding (Potential).
 MOTIF 392 401 SH3-binding (Potential).
 MOTIF 413 416 SH2-binding (Potential).  

Keyword

 Activator; Alternative splicing; Chromosomal rearrangement; Complete proteome; Nucleus; Proto-oncogene; Reference proteome; Repeat; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 418 AA 

Protein Sequence

Gene Ontology

 GO:0005881; C:cytoplasmic microtubule; IEA:Compara.
 GO:0005634; C:nucleus; TAS:ProtInc.
 GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
 GO:0000902; P:cell morphogenesis; IEA:Compara.
 GO:0048013; P:ephrin receptor signaling pathway; IEA:Compara.
 GO:0007243; P:intracellular protein kinase cascade; IEA:Compara.
 GO:0000226; P:microtubule cytoskeleton organization; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR007726; SSXT. 

Pfam

 PF05030; SSXT 

SMART

  

PROSITE

  

PRINTS