UniProt Accession

 MCAT_HUMAN; O43772; B2R7F4; Q9UIQ2 

Genbank Protein ID

 Y10319; Y17775; Y17776; Y17777; Y17778; Y17779; AK312962; BC001689 

Genbank Nucleotide ID

 CAA71367.1; CAB55356.1; CAB55356.1; CAB55356.1; CAB55356.1; CAB55356.1; BAG35801.1; AAH01689.1 

Protein Name

 Mitochondrial carnitine/acylcarnitine carrier protein 

Protein Synonyms/Alias

 Carnitine/acylcarnitine translocase; CAC; Solute carrier family 25 member 20 

Gene Name

 SLC25A20 

Gene Synonyms/Alias

 CAC; CACT 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
244	FQTAPPGKYPNGFRD	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. 

Sequence Annotation

 REPEAT 8 99 Solcar 1.
 REPEAT 108 196 Solcar 2.
 REPEAT 207 293 Solcar 3.
 MOD_RES 148 148 N6-acetyllysine (By similarity).
 MOD_RES 244 244 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Complete proteome; Disease mutation; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 301 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
 GO:0006853; P:carnitine shuttle; TAS:Reactome.
 GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
 GO:0044281; P:small molecule metabolic process; TAS:Reactome. 

Interpro

 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 

Pfam

 PF00153; Mito_carr 

SMART

  

PROSITE

 PS50920; SOLCAR 

PRINTS