CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028685
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Pdp1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
561VDHERLSKMLSLPEEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 597 AA 
Protein Sequence
MSISALLSMG RCCCRCCCPR GLWMLSAPCC DDRRMCVCPG PRRIGIPVRT SSLPLFSDAM 60
PAPTQLFFPL VRNCELSRIY GTACYCHHKH LCCSPPYIPQ NRLRYTPHPA YATFCRPREN 120
WWQYTQGRRY ASTPQKFYLT PPQVNSILKA NEYSFKVPEF DGKNVSSILG FDSNQLPANA 180
PIEDRRSAAT CLQTRGMLLG VFDGHAGCAC SQAVSERLFY YIAVSLLPHE TLLEIENAVE 240
SGRALLPILQ WHKHPNDYFS KEASKLYFNS LRTYWQELID LNTGESADID VKEALINAFK 300
RLDNDISLEA QVGDPNSFLN YLVLRVAFSG ATACVAHVDG VDLHVANTGD SRAMLGVQEE 360
DGSWSAVTLS NDHNAQNERE LERLKLEHPK NEAKSVVKQD RLLGLLMPFR AFGDVKFKWS 420
IDLQKRVIES GPDQLNDNEY TKFIPPNYHT PPYLTAEPEV TYHRLRPQDK FLVLATDGLW 480
ETMHRQDVVR IVGEYLTGMH HQQPIAVGGY KVTLGQMHGL LTERRAKMSS VFEDQNAATH 540
LIRHAVGNNE FGAVDHERLS KMLSLPEELA RMYRDDITII VVQFNSHVVG AYQNQEQ 597 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
 GO:0006470; P:protein dephosphorylation; IEA:InterPro. 
Interpro
 IPR001932; PP2C-like.
 IPR000222; PP2C_Mn2_Asp60_BS.
 IPR015655; Protein_Pase_2C. 
Pfam
 PF00481; PP2C 
SMART
 SM00331; PP2C_SIG
 SM00332; PP2Cc 
PROSITE
 PS01032; PP2C 
PRINTS