UniProt Accession

 F2Z420_MOUSE; F2Z420 

Genbank Protein ID

 AC152059; AL583892 

Genbank Nucleotide ID

  

Protein Name

 Histone-lysine N-methyltransferase setd3 

Protein Synonyms/Alias

  

Gene Name

 Setd3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
115	LRATRDIKAEELFLW	ubiquitination	[1]
211	HDVFSQYKNTARQYA	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 290 AA 

Protein Sequence

Gene Ontology

 GO:0000790; C:nuclear chromatin; IDA:MGI.
 GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:MGI.
 GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:MGI.
 GO:0003713; F:transcription coactivator activity; IEA:InterPro.
 GO:0051149; P:positive regulation of muscle cell differentiation; IMP:MGI.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI. 

Interpro

 IPR025785; Hist-Lys_N-MeTrfase_SETD3.
 IPR001214; SET_dom. 

Pfam

 PF00856; SET 

SMART

  

PROSITE

 PS51565; SAM_MT43_SETD3 

PRINTS