CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011164
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uridine nucleosidase 
Protein Synonyms/Alias
 Uridine ribohydrolase 
Gene Name
 URH1 
Gene Synonyms/Alias
 YDR400W; D9509.19 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
221NEMIYNEKNNSKLREubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Also acts on cytidine. 
Sequence Annotation
 ACT_SITE 254 254 By similarity.  
Keyword
 Complete proteome; Cytoplasm; Glycosidase; Hydrolase; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 340 AA 
Protein Sequence
MTVSKIPIWL DCDPGHDDAI AILLGCFHPA FNLLGISTCF GNAPPENTDY NARSLLTAMG 60
KAQAIPVYKG AQRPWKREPH YAPDIHGISG LDGTSLLPKP TFEARTDKTY IEAIEEAILA 120
NNGEISFVST GALTTLATVF RCKPYLKKSV KYISIMGGGL HGLGNCNPNL SAEFNVWIDP 180
DAANYIFRDP DVKDKCIVVP LNLTHKAIAT YKVNEMIYNE KNNSKLRELF LELFQFFAHT 240
YKDMQGFESG PPIHDPVALM PLLEFYGWDP SSAVGFRYKR MDISCIDDVF NENSGKIIIE 300
KEYPNDSDVG TIIGLDLNIQ YFWDQIFEAL NRADKMSTIG 340 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0070635; F:nicotinamide riboside hydrolase activity; IDA:SGD.
 GO:0070636; F:nicotinic acid riboside hydrolase activity; IDA:SGD.
 GO:0045437; F:uridine nucleosidase activity; IDA:SGD.
 GO:0006216; P:cytidine catabolic process; IMP:SGD.
 GO:0034356; P:NAD biosynthesis via nicotinamide riboside salvage pathway; IGI:SGD.
 GO:0019358; P:nicotinate nucleotide salvage; IGI:SGD.
 GO:0008655; P:pyrimidine-containing compound salvage; IMP:SGD.
 GO:0006218; P:uridine catabolic process; IMP:SGD. 
Interpro
 IPR015910; I/U_nuclsd_hydro_CS.
 IPR023186; Inosine/uridine_hydrolase.
 IPR001910; Inosine/uridine_hydrolase_dom. 
Pfam
 PF01156; IU_nuc_hydro 
SMART
  
PROSITE
 PS01247; IUNH 
PRINTS