CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027054
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Aos1 
Protein Synonyms/Alias
 CG12276 protein; CG12276-PA; LD33652p 
Gene Name
 Aos1 
Gene Synonyms/Alias
 CG12276; Dmel_CG12276 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
183SYVEDVIKHKVVANSacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 337 AA 
Protein Sequence
MVVDMDTSET AVELTEAENE LYDRQIRLWG LESQKRLRTA KILIAGLCGL GAEITKNIIL 60
SGVNSVKLLD DKDVTEEDFC SQFLVPRESL NTNRAEASLT RARALNPMVD ISADREPLKE 120
KTSEFFGQFD VVVVNGATNE ELLRIDTICR DLGVKFIATD VWGTFGFYFA SLQKHSYVED 180
VIKHKVVANS EKKKKYETVS IPTQRDVDYP GYSAWLDFDV TEPSYLRKLK RNGPGVLLLS 240
VLQKFRTTHK RDPSYKTREA DLELLRGIRD ELLPNSILGD EALGLIFAQI SPAVAVVGGV 300
VAQEVIKVVT KLEAPHRNLF VFDPETCAGY VEAIGAK 337 
Gene Ontology
 GO:0031510; C:SUMO activating enzyme complex; ISS:FlyBase.
 GO:0019948; F:SUMO activating enzyme activity; ISS:FlyBase.
 GO:0022008; P:neurogenesis; IMP:FlyBase.
 GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:FlyBase.
 GO:0016925; P:protein sumoylation; IMP:FlyBase.
 GO:0007346; P:regulation of mitotic cell cycle; IMP:FlyBase. 
Interpro
 IPR009036; Molybdenum_cofac_synth_MoeB.
 IPR016040; NAD(P)-bd_dom.
 IPR000594; ThiF_NAD_FAD-bd.
 IPR000011; UBQ/SUMO-activ_enz_E1-like. 
Pfam
 PF00899; ThiF 
SMART
  
PROSITE
  
PRINTS
 PR01849; UBIQUITINACT.