UniProt Accession

 SRSF3_MOUSE; P84104; O08831; P23152; Q564E9 

Genbank Protein ID

 X53824; X91656; X91656; AK011657; AK078891; AK134177; AK135298; AK145089; AK145715; AK146010; AK146253; AK150912; AK153209; BC068111; BC071196; BC083316 

Genbank Nucleotide ID

 CAA37821.1; CAA62844.1; CAA62845.1; BAB27762.1; BAC37445.1; BAE22040.1; BAE22483.1; BAE26230.1; BAE26606.1; BAE26830.1; BAE27015.1; BAE29950.1; BAE31808.1; AAH68111.1; AAH71196.1; AAH83316.1 

Protein Name

 Serine/arginine-rich splicing factor 3 

Protein Synonyms/Alias

 Pre-mRNA-splicing factor SRP20; Protein X16; Splicing factor, arginine/serine-rich 3 

Gene Name

 Srsf3 

Gene Synonyms/Alias

 Sfrs3; Srp20; X16 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
23	NLGNNGNKTELERAF	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 May be involved in RNA processing in relation with cellular proliferation and/or maturation. 

Sequence Annotation

 DOMAIN 10 83 RRM.
 REPEAT 119 133 B-1.
 REPEAT 149 164 B-2.
 REGION 119 164 2 X approximate repeats, basic.
 MOD_RES 1 1 N-acetylmethionine (By similarity).
 MOD_RES 5 5 Phosphoserine (By similarity).
 MOD_RES 23 23 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Alternative splicing; Complete proteome; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; RNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 164 AA 

Protein Sequence

Gene Ontology

 GO:0016607; C:nuclear speck; IDA:BHF-UCL.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; TAS:BHF-UCL.
 GO:0008286; P:insulin receptor signaling pathway; TAS:BHF-UCL.
 GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
 GO:0008380; P:RNA splicing; TAS:BHF-UCL. 

Interpro

 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 

Pfam

 PF00076; RRM_1 

SMART

 SM00360; RRM 

PROSITE

 PS50102; RRM 

PRINTS