CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024064
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Prenylated Rab acceptor protein 1 
Protein Synonyms/Alias
 PRA1 family protein 1; Prenylin 
Gene Name
 Rabac1 
Gene Synonyms/Alias
 Pra; Pra1; Praf1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
24SATTLLPKLIPSGAGubiquitination[1]
118YLRTLQSKLVLFGREubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI1 (By similarity). 
Sequence Annotation
 REGION 30 54 Required for interaction with prenylated
 REGION 165 185 Required for interaction with GDI1 (By
 REGION 175 185 Homodimerization.
 REGION 175 185 Required for interaction with prenylated  
Keyword
 Cell junction; Cell membrane; Complete proteome; Cytoplasm; Cytoplasmic vesicle; Golgi apparatus; Membrane; Reference proteome; Synapse; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 185 AA 
Protein Sequence
MAAQKDQQKD AEGEGLSATT LLPKLIPSGA GREWLERRRA TIRPWGTFVD QQRFSRPRNV 60
GELCQRLVRN VEYYQSNYVF VFLGLILYCV VTSPMLLVAL AVFFGACYIL YLRTLQSKLV 120
LFGREVSPAH QYALAGGVSF PFFWLAGAGS AVFWVLGATL VLIGSHAAFH QMEPADGEEL 180
QMEPV 185 
Gene Ontology
 GO:0030054; C:cell junction; IEA:UniProtKB-KW.
 GO:0005794; C:Golgi apparatus; IDA:MGI.
 GO:0016021; C:integral to membrane; IDA:MGI.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0008021; C:synaptic vesicle; IEA:UniProtKB-SubCell. 
Interpro
 IPR004895; Prenylated_rab_accept_PRA1. 
Pfam
 PF03208; PRA1 
SMART
  
PROSITE
  
PRINTS