CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004771
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA-binding protein HU 
Protein Synonyms/Alias
 DNA-binding protein II; TL29 
Gene Name
 TTHA1349 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) 
NCBI Taxa ID
 300852 
Lysine Modification
Position
Peptide
Type
References
36MVDALLAKVEEALANacetylation[1]
Reference
 [1] Acetylome with structural mapping reveals the significance of lysine acetylation in Thermus thermophilus.
 Okanishi H, Kim K, Masui R, Kuramitsu S.
 J Proteome Res. 2013 Aug 1;. [PMID: 23901841
Functional Description
 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. 
Sequence Annotation
  
Keyword
 Complete proteome; Direct protein sequencing; DNA condensation; DNA-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 96 AA 
Protein Sequence
AAKKTVTKAD LVDQVAQATG LKKKDVKAMV DALLAKVEEA LANGSKVQLT GFGTFEVRKR 60
KARTGVKPGT KEKIKIPATQ YPAFKPGKAL KDKVKK 96 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW. 
Interpro
 IPR023630; DNA-bd_HU/IHF.
 IPR000119; Hist_DNA-bd_bac.
 IPR020816; Histone-like_DNA-bd_CS.
 IPR010992; IHF-like_DNA-bd_dom. 
Pfam
 PF00216; Bac_DNA_binding 
SMART
 SM00411; BHL 
PROSITE
 PS00045; HISTONE_LIKE 
PRINTS
 PR01727; DNABINDINGHU.