UniProt Accession

 NAGD_ECOLI; P0AF24; P15302 

Genbank Protein ID

 X14135; AF052007; U00096; AP009048 

Genbank Nucleotide ID

 CAA32355.1; AAC09327.1; AAC73769.1; BAA35318.1 

Protein Name

 Ribonucleotide monophosphatase NagD 

Protein Synonyms/Alias

  

Gene Name

 nagD 

Gene Synonyms/Alias

 b0675; JW0661 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
129	YNWDMMHKAAYFVAN	acetylation	[1]
165	ALCAGIEKISGRKPF	acetylation	[1]
170	IEKISGRKPFYVGKP	acetylation	[1]
176	RKPFYVGKPSPWIIR	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Catalyzes the dephosphorylation of an unusually broad range of substrate including deoxyribo- and ribonucleoside tri-, di-, and monophosphates, as well as polyphosphate and glucose-1-P (Glu1P). 

Sequence Annotation

 REGION 42 43 Substrate binding.
 REGION 202 205 Substrate binding.
 ACT_SITE 11 11
 METAL 9 9 Magnesium.
 METAL 11 11 Magnesium; via carbonyl oxygen.
 METAL 201 201 Magnesium.
 BINDING 11 11 Substrate.
 BINDING 176 176 Substrate.  

Keyword

 3D-structure; Carbohydrate metabolism; Complete proteome; Hydrolase; Magnesium; Metal-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 250 AA 

Protein Sequence

Gene Ontology

 GO:0008253; F:5'-nucleotidase activity; IDA:UniProtKB.
 GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
 GO:0005975; P:carbohydrate metabolic process; TAS:EcoCyc.
 GO:0034655; P:nucleobase-containing compound catabolic process; IDA:EcoCyc. 

Interpro

 IPR023214; HAD-like_dom.
 IPR006357; HAD-SF_hydro_IIA.
 IPR023215; NPhePase-like_dom. 

Pfam

 PF00702; Hydrolase 

SMART

  

PROSITE

  

PRINTS