CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016505
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pumilio domain-containing protein KIAA0020 
Protein Synonyms/Alias
  
Gene Name
 Kiaa0020 
Gene Synonyms/Alias
 D19Bwg1357e 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
33NSESSSSKTFPRKAVacetylation[1]
92NKFSKKRKFQPDGESacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
 DOMAIN 142 509 PUM-HD.
 REPEAT 164 199 Pumilio 1.
 REPEAT 200 235 Pumilio 2.
 REPEAT 236 272 Pumilio 3.
 REPEAT 349 384 Pumilio 4.
 REPEAT 385 421 Pumilio 5.
 REPEAT 423 459 Pumilio 6.  
Keyword
 Complete proteome; Nucleus; Reference proteome; Repeat; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 647 AA 
Protein Sequence
MEVKGKKKFT GKSPQTSQGK NKFHKNSESS SSKTFPRKAV KEGGPKVTSK NFEKGATKPG 60
KKGVKQFKNK PQGGKGPKDK FQKANKFSKK RKFQPDGESD ESGAKKPKWD DFKKKKKELK 120
QSRQLSDKTN YDIVVRAKHI WESLRRKDCD KEKRVKLMSD LQKLIQGKIK TIAFAHDSTR 180
VIQCFIQYGN EEQRKQAFQE LQGDLVELSK AKYSRNIVKK FLMYGSKPQV AEIIRSFKGH 240
VRKMLRHSEA SAIVEYAYND KAILEQRNML TEELYGNTFQ LYKSADHPTL DKVLELQPAK 300
LELIMDEMKQ ILTPMAQKEA VIKHSLVHKV FLDFFTYAPP KPRSELIEAI REAVVYLAHT 360
HDGARVAMHC LWHGTPKDRK VIVKTMKTYV EKVANGQYSH LVLLAAFDCI DDTKLVKQII 420
ISEIISSLPS IVNDKYGRKV LLYLMSPRDP AHTVPELIEL LQKGDGNAHS KKDTAIRRRE 480
LLESISPALL SYLQGHTQEV VLDKSACVLV SDMLGSATGD VQPAMDAIAS LAAAELHPGG 540
KDGELHVAEH PAGHLVLKWL LEQDKKMKES GKEGCFAKTL VERVGMKNLK SWASINRGAI 600
ILSSLLQSCD QEVVNKVKGG LKPLIPTLEK NKSSSRGIQT LLEKLTA 647 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR012959; CPL.
 IPR001313; Pumilio_RNA-bd_rpt. 
Pfam
 PF08144; CPL 
SMART
 SM00025; Pumilio 
PROSITE
 PS50302; PUM
 PS50303; PUM_HD 
PRINTS