CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000488
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Guanine nucleotide-binding protein subunit beta-like protein 
Protein Synonyms/Alias
 Receptor of activated protein kinase C homolog 
Gene Name
 Rack1 
Gene Synonyms/Alias
 CG7111 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
131GSRDKTIKLWNTLAEacetylation[1]
266IWDLACKKTVEELRPacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
 REPEAT 13 44 WD 1.
 REPEAT 62 92 WD 2.
 REPEAT 104 134 WD 3.
 REPEAT 147 179 WD 4.
 REPEAT 191 221 WD 5.
 REPEAT 232 261 WD 6.
 REPEAT 282 312 WD 7.  
Keyword
 3D-structure; Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 318 AA 
Protein Sequence
MSETLQLRGT LIGHNGWVTQ IATNPKDPDT IISASRDKTL IVWKLTRDED TNYGYPQKRL 60
YGHSHFISDV VLSSDGNYAL SGSWDQTLRL WDLAAGKTTR RFEGHTKDVL SVAFSADNRQ 120
IVSGSRDKTI KLWNTLAECK FTIQEDGHTD WVSCVRFSPN HSNPIIVSCG WDRTVKVWNL 180
ANCKLKNNHH GHNGYLNTVT VSPDGSLCTS GGKDSKALLW DLNDGKNLYT LEHNDIINAL 240
CFSPNRYWLC VAYGPSIKIW DLACKKTVEE LRPEVVSPTS KADQPQCLSL AWSTDGQTLF 300
AGYSDNTIRV WQVSVSAH 318 
Gene Ontology
 GO:0005776; C:autophagic vacuole; IDA:FlyBase.
 GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.
 GO:0042335; P:cuticle development; IMP:FlyBase.
 GO:0007626; P:locomotory behavior; IMP:FlyBase.
 GO:0000398; P:mRNA splicing, via spliceosome; IC:FlyBase.
 GO:0046716; P:muscle cell homeostasis; IGI:FlyBase.
 GO:0048477; P:oogenesis; IMP:FlyBase.
 GO:0018991; P:oviposition; IMP:FlyBase.
 GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:FlyBase.
 GO:0016243; P:regulation of autophagic vacuole size; IMP:FlyBase.
 GO:0035220; P:wing disc development; IMP:FlyBase. 
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.