CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038620
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Immunoglobulin superfamily-containing leucine-rich repeat protein 2 
Protein Synonyms/Alias
  
Gene Name
 Islr2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
683QAPDPMEKRIAADFDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Immunoglobulin domain; Leucine-rich repeat; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 789 AA 
Protein Sequence
MHSPFLPTAT ATDARSSLRL SPESGDRLAA PQHHTASQRA AGVTMGPFGA LCLAWALLGV 60
VRACPEPCAC VDKYAHQFAD CAYKELREVP EGLPANVTTL SLSANKITVL RRGAFVNVTQ 120
VTSLWLAHSE VRTVESGALA VLSQLKNLDL SHNLISNFPW SDLRNLSALQ LLKMNHNRLG 180
SLPRDALGAL PDLRSLRINN NRLRTLEPGT FDALSALSHL QLYHNPFHCS CGLVWLQAWA 240
ASTRVSLPEP DSIACASPPE LQGVPVHRLP ALPCAPPSVR LSAEPPPEAP GTPLRAGLAF 300
MLHCVAEGHP TPRLQWQLQI PGGTVVLVPP VLSKEEDGGD KVEDGEGDGD EDLPTQTEAP 360
TPTPAPAWPA PPATPRFLAL ANGSLLVPLL SAKEAGIYTC RAHNELGTNS TSLRVTVAAA 420
GPPKHAPGTG EEPDAQVPTS ERKATTKGRS NSVLPFKPEG KTKGQGLARV SVLGEIEAEL 480
EETDEGEQME GQIPADPMGE KHCGHGDPSR YVSNHAFNQS SDLKPHVFEL GVIALDVAER 540
EARVQLTPLA ARWGPGPDGA SGARRPGRRP LRLLYLCPAG GGTAVQWSRV EEGVNAYWFR 600
GLRPGTNYSV CLALAGEACH VQVVFSTKKE LPSLLVIVTV SVFLLVLATV PLLGAACCHL 660
LAKHPGKPYR LILRPQAPDP MEKRIAADFD PRASYLESEK SYPARGEAGG EEPEEVPEEG 720
LDEDVEQGDP SGDLQREESL AGCSLVESQS KANQEEFEAG SEYSDRLPLG AEAVNIAQEI 780
NGNYRQTAG 789 
Gene Ontology
  
Interpro
 IPR000483; Cys-rich_flank_reg_C.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub.
 IPR001611; Leu-rich_rpt.
 IPR003591; Leu-rich_rpt_typical-subtyp.
 IPR000372; LRR-contain_N. 
Pfam
  
SMART
 SM00409; IG
 SM00369; LRR_TYP
 SM00082; LRRCT
 SM00013; LRRNT 
PROSITE
 PS50835; IG_LIKE
 PS51450; LRR 
PRINTS