UniProt Accession

 F6UB20_MOUSE; F6UB20 

Genbank Protein ID

 AC131992 

Genbank Nucleotide ID

  

Protein Name

 MOSC domain-containing protein 2, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 Marc2 

Gene Synonyms/Alias

 Mosc2 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
56	QQVGTVSKVWIYPIK	ubiquitination	[1]
63	KVWIYPIKSCKGVSV	phosphoglycerylation	[2]
63	KVWIYPIKSCKGVSV	ubiquitination	[1]
66	IYPIKSCKGVSVCET	ubiquitination	[1]
94	DRFWMVVKEDGHMVT	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Functional lysine modification by an intrinsically reactive primary glycolytic metabolite.
 Moellering RE, Cravatt BF.
 Science. 2013 Aug 2;341(6145):549-53. [PMID: 23908237] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 277 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
 GO:0003824; F:catalytic activity; IEA:InterPro.
 GO:0030151; F:molybdenum ion binding; IEA:InterPro.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0008152; P:metabolic process; IEA:GOC. 

Interpro

 IPR005302; MoCF_Sase_C.
 IPR005303; MOSC_N. 

Pfam

 PF03473; MOSC
 PF03476; MOSC_N 

SMART

  

PROSITE

 PS51340; MOSC 

PRINTS