CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024975
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sodium channel beta4 subunit 
Protein Synonyms/Alias
 Sodium channel, type IV, beta 
Gene Name
 Scn4b 
Gene Synonyms/Alias
 SCN4B 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
199KKTREKKKECLVSSSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Ion channel; Ion transport; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 228 AA 
Protein Sequence
MSRAGNRGNT QARWLGTGLL GLFLLPMYLS LEVSVGKATT IYAINGSSIL LPCTFSSCYG 60
FENLYFKWSY NNSETSRILI DGIVKNDKSD PKVRVKDDDR ITLEGSTKEK TNNISILLSD 120
LEFSDTGRYT CFVRNPKEKD LNNSATIFLQ VVDKLEKVDN TVTLIILAVV GGVIGLLVCI 180
LLLKKLITFI LKKTREKKKE CLVSSSGNDN TENGLPGSKA EEKPPTKV 228 
Gene Ontology
 GO:0001518; C:voltage-gated sodium channel complex; IC:MGI.
 GO:0017080; F:sodium channel regulator activity; IEA:Compara.
 GO:0005248; F:voltage-gated sodium channel activity; IMP:MGI.
 GO:0086006; F:voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential; IEA:Compara.
 GO:0086067; P:AV node cell to bundle of His cell communication; IEA:Compara.
 GO:0060048; P:cardiac muscle contraction; IEA:Compara.
 GO:0010765; P:positive regulation of sodium ion transport; IEA:Compara.
 GO:0086002; P:regulation of cardiac muscle cell action potential involved in contraction; IEA:Compara.
 GO:0086091; P:regulation of heart rate by cardiac conduction; IEA:Compara.
 GO:2000649; P:regulation of sodium ion transmembrane transporter activity; IEA:Compara.
 GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; IEA:Compara. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub.
 IPR013106; Ig_V-set. 
Pfam
 PF07686; V-set 
SMART
 SM00409; IG 
PROSITE
 PS50835; IG_LIKE 
PRINTS