CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030833
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Prostaglandin E synthase 3 
Protein Synonyms/Alias
 cDNA FLJ59888, moderately similar to Prostaglandin E synthase 3 (EC 5.3.99.3) 
Gene Name
 PTGES3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
35NVNFEKSKLTFSCLGacetylation[1]
35NVNFEKSKLTFSCLGubiquitination[1, 2, 3]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 127 AA 
Protein Sequence
MQPASAKWYD RRDYVFIEFC VEDSKDVNVN FEKSKLTFSC LGGSDNFKHL NEIDLFHCID 60
PNLNWLSVDF NNWKDWEDDS DEDMSNFDRF SEMMNNMGGD EDVDLPEVDG ADDDSQDSDD 120
EKMPDLE 127 
Gene Ontology
  
Interpro
 IPR007052; CS-like_domain.
 IPR017447; CS_domain.
 IPR008978; HSP20-like_chaperone. 
Pfam
 PF04969; CS 
SMART
  
PROSITE
 PS51203; CS 
PRINTS