CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029800
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Serine/threonine-protein kinase PAK 3 
Protein Synonyms/Alias
  
Gene Name
 PAK3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
145LQTSNITKLEQKKNPubiquitination[1, 2]
149NITKLEQKKNPQAVLubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 181 AA 
Protein Sequence
MSDGLDNEEK PPAPPLRMNS NNRDSSALNH SSKPLPMAPE EKNKKARLRS IFPGGGDKTN 60
KKKEKERPEI SLPSDFEHTI HVGFDAVTGE FTNSPFQTSR PVTVASSQSE GKMPDLYGSQ 120
MCPGKLPEGI PEQWARLLQT SNITKLEQKK NPQAVLDVLK FYDSKETVNN QKYMSFTSGD 180
K 181 
Gene Ontology
 GO:0004672; F:protein kinase activity; IEA:Compara.
 GO:0007409; P:axonogenesis; IEA:Compara.
 GO:0016358; P:dendrite development; IEA:Compara.
 GO:0006468; P:protein phosphorylation; IEA:GOC. 
Interpro
 IPR000095; PAK_box_Rho-bd. 
Pfam
 PF00786; PBD 
SMART
 SM00285; PBD 
PROSITE
 PS50108; CRIB 
PRINTS