UniProt Accession

 E9PC44_HUMAN; E9PC44; B3KWV9 

Genbank Protein ID

 AC108030; AC110079; AK125962 

Genbank Nucleotide ID

 BAG54271.1 

Protein Name

 Protein transport protein Sec24D 

Protein Synonyms/Alias

 cDNA FLJ43974 fis, clone TESTI4018101, highly similar to Protein transport protein Sec24D 

Gene Name

 SEC24D 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
132	KAADCPGKLFIFHSS	ubiquitination	[1]
150	AEAPGKLKNRDDKKL	ubiquitination	[1]
240	LRNDIEKKIGFDAIM	ubiquitination	[1]
347	ALINFFAKSAFKAVL	ubiquitination	[1, 2]
351	FFAKSAFKAVLHQPL	ubiquitination	[3]
359	AVLHQPLKVIREILV	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 393 AA 

Protein Sequence

Gene Ontology

 GO:0030127; C:COPII vesicle coat; IEA:InterPro.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro. 

Interpro

 IPR006900; Sec23/24_helical_dom.
 IPR006896; Sec23/24_trunk_dom.
 IPR012990; Sec23_24_beta_S.
 IPR002035; VWF_A. 

Pfam

 PF08033; Sec23_BS
 PF04815; Sec23_helical
 PF04811; Sec23_trunk 

SMART

  

PROSITE

  

PRINTS