CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038406
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Probable E3 ubiquitin-protein ligase DTX3 
Protein Synonyms/Alias
  
Gene Name
 Dtx3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
223NGRMLVSKDATLLLPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 395 AA 
Protein Sequence
MSFVLSRMAA CGGSCKNKVT VSKPVWDFLS KETPARLARL REEHRVSILI DGETSDIYVL 60
QLSPQGPPPA PPNGLYLARK ALKGLLKEAE KELKKAQRQG ELMGCLALGG GGEHPELHRP 120
GPPPLRAAPL LPPGARGLPP PPPPLPPPLP PRLREDAEEQ ETTCPICLGE IQNAKTLEKC 180
RHSFCEGCIT RALQVKKACP MCGRFYGQLV GNQPQNGRML VSKDATLLLP SYEKYGTIVI 240
QYVFPPGVQG AEHPNPGVRY PGTTRVAYLP DCPEGNKVLT LFRKAFDQRL TFTIGTSMTT 300
GRPNVITWND IHHKTSCTGG PQLCDSSSSP SPWRLPFTIS NLGEPSTLSV CFHPGPDAFS 360
LTPPLPTQKA YSGWVILVLE VPPHGKWEGS EFGPN 395 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0007219; P:Notch signaling pathway; IDA:MGI. 
Interpro
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
  
SMART
 SM00184; RING 
PROSITE
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2 
PRINTS