UniProt Accession

 C9J461_HUMAN; C9J461 

Genbank Protein ID

 AC108679; AC112504; AC128648; AC133435 

Genbank Nucleotide ID

  

Protein Name

 Transcription factor Dp-2 

Protein Synonyms/Alias

  

Gene Name

 TFDP2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
49	GDRKRARKFIDSDFS	ubiquitination	[1, 2]
59	DSDFSESKRSKKGDK	ubiquitination	[1, 2]
117	ADSAYDQKNIRRRVY	ubiquitination	[1]
144	SKEKKEIKWIGLPTN	ubiquitination	[1, 2]
163	CQNLEIEKQRRIERI	ubiquitination	[1, 2]
188	LLQQIAFKNLVQRNR	ubiquitination	[1, 2, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 220 AA 

Protein Sequence

Gene Ontology

 GO:0005667; C:transcription factor complex; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0007507; P:heart development; IEA:Compara.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR003316; E2F_TDP.
 IPR014889; Transc_factor_DP_C.
 IPR015648; Transcrpt_fac_DP.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF08781; DP
 PF02319; E2F_TDP 

SMART

  

PROSITE

  

PRINTS