UniProt Accession

 YFCF_ECOLI; P77544 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC75361.1; BAA16138.1 

Protein Name

 Glutathione S-transferase YfcF 

Protein Synonyms/Alias

  

Gene Name

 yfcF 

Gene Synonyms/Alias

 b2301; JW2298 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
36	KGLSFHIKTIDLDSG	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Exhibits glutathione (GSH) S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB); however this activity is as low as 1% of that of GstA. Also displays a GSH-dependent peroxidase activity toward cumene hydroperoxide. Is involved in defense against oxidative stress, probably via its peroxidase activity. 

Sequence Annotation

 DOMAIN 6 87 GST N-terminal.
 DOMAIN 95 214 GST C-terminal.  

Keyword

 3D-structure; Complete proteome; Oxidoreductase; Peroxidase; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 214 AA 

Protein Sequence

Gene Ontology

 GO:0004364; F:glutathione transferase activity; IDA:EcoCyc.
 GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
 GO:0042542; P:response to hydrogen peroxide; IMP:EcoCyc. 

Interpro

 IPR010987; Glutathione-S-Trfase_C-like.
 IPR004045; Glutathione_S-Trfase_N.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR012336; Thioredoxin-like_fold. 

Pfam

  

SMART

  

PROSITE

 PS50405; GST_CTER
 PS50404; GST_NTER 

PRINTS