CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027389
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP-dependent DNA helicase, putative 
Protein Synonyms/Alias
  
Gene Name
 PF13_0330 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
366YKHQDILKILEQRAEacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 483 AA 
Protein Sequence
MKLEEVKDIQ KIERIGAHSH IRGLGLNDCL DARYCSEGMI GQMSARKAAG IVLRMIKEGR 60
ISGRAILLAG QPGTGKTAIA MGIAKALGED TPFTHISGSE VYSLEMSKTE ALTQAFRRSI 120
GVRVKEESEV IEGEVVEIEI EKFNERDINN KNKKLGKMIL KTTEMETLYD LGSKMIEALQ 180
KENITAGDVI CIDKGTGKIT KIGKSFARSK DYDAMDPNTL FVQCPEGELQ KRKEVVHTVT 240
LHDIDAINSR TQGFLALFSG DTGEIKNEIR EHIDMKINEW QEDEKAEIVP GVLFIDEVHM 300
LDIECFSYLN RALESEQSPI VIMATNRGIT HIRGTDYKAP HGIPLDLLDR TLIIPTYPYK 360
HQDILKILEQ RAEEEDVDID EYAKELLCKI ASESSLRYAL HLITLANLVS KKRKATEVTV 420
QDVRRVYNLF IDVKRSTQYL IEYQNEFMFS ELPKEELSVK EEDSSEEKRE LHEKNSENSS 480
TSN 483 
Gene Ontology
 GO:0031011; C:Ino80 complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0043141; F:ATP-dependent 5'-3' DNA helicase activity; IEA:InterPro.
 GO:0004003; F:ATP-dependent DNA helicase activity; ISS:GeneDB_Pfalciparum. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR012340; NA-bd_OB-fold.
 IPR027417; P-loop_NTPase.
 IPR027238; RuvB-like.
 IPR010339; TIP49_C. 
Pfam
 PF06068; TIP49 
SMART
 SM00382; AAA 
PROSITE
  
PRINTS