CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040826
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Argininosuccinate lyase 
Protein Synonyms/Alias
  
Gene Name
 ASL 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
32TANERRLKELIGATAubiquitination[1]
41LIGATAGKLHTGRSRubiquitination[1]
222GSSLMPQKKNPDSLEubiquitination[1]
223SSLMPQKKNPDSLELubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 242 AA 
Protein Sequence
MASEVAEEWA QGTFKLNSND EDIHTANERR LKELIGATAG KLHTGRSRND QVVTDLRLWM 60
RQTCSTLSGL LWELIRTMVD RAEAERDVLF PGYTHLQRAQ PIRWSHWILS HAVALTRDSE 120
RLLEVRKRIN VLPLGSGAIA GNPLGVDREL LRAELNFGAI TLNSMDATSE RDFVAEFLFW 180
ASLCMTHLSR MAEDLILYCT KEFSFVQLSD AYSTGSSLMP QKKNPDSLEL IRSKAGRVFG 240
RV 242 
Gene Ontology
 GO:0004056; F:argininosuccinate lyase activity; IEA:InterPro.
 GO:0042450; P:arginine biosynthetic process via ornithine; IEA:InterPro. 
Interpro
 IPR009049; Argininosuccinate_lyase.
 IPR003031; D_crystallin.
 IPR024083; Fumarase/histidase_N.
 IPR000362; Fumarate_lyase.
 IPR020557; Fumarate_lyase_CS.
 IPR022761; Fumarate_lyase_N.
 IPR008948; L-Aspartase-like. 
Pfam
 PF00206; Lyase_1 
SMART
  
PROSITE
 PS00163; FUMARATE_LYASES 
PRINTS
 PR00145; ARGSUCLYASE.
 PR00149; FUMRATELYASE.