CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025827
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protocadherin beta 5 variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
768AGEFKFLKPIIPNLLubiquitination[1]
785GAGEEIGKTAAFRNSubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
 Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (By similarity). 
Sequence Annotation
  
Keyword
 Calcium; Cell adhesion; Cell membrane; Membrane; Repeat; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 796 AA 
Protein Sequence
TMETALAKTP QKRQVMFLAI LLLLWEAGSE AVRYSIPEET ESGYSVANLA KDLGLGVGEL 60
ATRGARMHYK GNKELLQLDI KTGNLLLYEK LDREVMCGAT EPCILHFQLL LENPVQFFQT 120
DLQLTDINDH APEFPEKEML LKIPESTQPG TVFPLKIAQD FDIGSNTVQN YTISPNSHFH 180
VATHNRGDGR KYPELVLDKA LDREERPELS LTLTALDGGA PPRSGTTTIR IVVLDNNDNA 240
PEFLQSFYEV QVPENSPLNS LVVVVSARDL DAGAYGSVAY ALFQGDEVTQ PFVIDEKTAE 300
IRLKRALDFE ATPYYNVEIV ATDGGGLSGK CTVAIEVVDV NDNAPELTMS TLSSPTPENA 360
PETVVAVFSV SDPDSGDNGR MICSIQNDLP FLLKPTLKNF YTLVTQRTLD RESQAEYNIT 420
ITVTDMGTPR LKTEHNITVL VSDVNDNAPA FTQTSYTLFV RENNSPALHI GSVSATDRDS 480
GTNAQVTYSL LPPQNPHLRL ASLVSINADN GHLFALRSLD YEALQAFEFR VGATDRGSPA 540
LSSEALVRVL VLDANDNSPF VLYPLQNGSA PCTELVPRAA EPGYLVTKVV AVDGDSGQNA 600
WLSYQLLKAT EPGLFSMWAH NGEVRTARLL SERDAAKHRL VVLVKDNGEP PRSATATLHV 660
LLVDGFSQPY LPLPEAAPAQ AQADSLTVYL VVALASVSSL FLFSVLLFVA VRLCRRSRAA 720
PVGRCSVPEG PFPGHLVDVS GTGTLSQSYH YEVCLTGDSG AGEFKFLKPI IPNLLPQGAG 780
EEIGKTAAFR NSFGLN 796 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0007156; P:homophilic cell adhesion; IEA:InterPro. 
Interpro
 IPR002126; Cadherin.
 IPR015919; Cadherin-like.
 IPR020894; Cadherin_CS.
 IPR013164; Cadherin_N. 
Pfam
 PF00028; Cadherin
 PF08266; Cadherin_2 
SMART
 SM00112; CA 
PROSITE
 PS00232; CADHERIN_1
 PS50268; CADHERIN_2 
PRINTS
 PR00205; CADHERIN.