CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027701
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Gbp6 protein 
Protein Synonyms/Alias
 Guanylate binding protein 7; MCG141961, isoform CRA_a; Protein Gbp7 
Gene Name
 Gbp7 
Gene Synonyms/Alias
 Gbp6; mCG_141961 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
381DENQQFQKNLVVTIEubiquitination[1]
510ELLRQKQKELQQVMEubiquitination[1]
524EAQERSYKENVAQLHubiquitination[1]
565DMLNEGFKRKCEAMDubiquitination[1]
613SVVPGSGKYFGLGLKubiquitination[1]
620KYFGLGLKILSSQMNubiquitination[1]
634NQTQNSDKVRKL***ubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 638 AA 
Protein Sequence
MASGPNMEAP VCLVENENEE LRVNSKAINI LERITQPVVV VAIVGLYRTG KSYLMNRLAG 60
QNHGFNLGTT VRSETKGIWM WCVPHPSKPK FTLVLLDTEG LGDVEKGDPK NDSWIFALAV 120
LLSSTFVYNS MSTINHQALE QLHYVTELTE RIRAKSTSRS EEVDDSDEFV SFFPDFIWTV 180
RDFVLELKLE GRVITADEYL ENALKLIPGM SIKAQKANLP RECIRHFFPR RKCFVFDRPT 240
KDKELLVHVE EMPEDQLDHS FQVQSKEFCS YIFSNSKAKT LKEGIVVNGN RLATLVTTYV 300
DAINSGDVPC LENAVTTLAQ RENSIAVQKA ADHYSEQMAQ RMRLPTDTLQ ELLTVHTACE 360
KEAIAVFMEH SFKDENQQFQ KNLVVTIEEK KEDFLRQNEA ASLSHCQAEL DKLSESLRES 420
ISRGVFSVPG GHRLYLEARK KVEQDYERVP RKGVKANHVL QSFLQSQISI EDSIMQSDKA 480
LTDGQKAMEA ERAQKEAAEK EQELLRQKQK ELQQVMEAQE RSYKENVAQL HEKMETERKN 540
ILREQEVKLE HKLKIQKDML NEGFKRKCEA MDLEISQLQK EIQLNKEKNS SLGAKILDGF 600
GDVLISVVPG SGKYFGLGLK ILSSQMNQTQ NSDKVRKL 638 
Gene Ontology
 GO:0031410; C:cytoplasmic vesicle; IDA:MGI.
 GO:0020005; C:symbiont-containing vacuole membrane; IDA:MGI.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0051856; P:adhesion to symbiont; IDA:MGI.
 GO:0071346; P:cellular response to interferon-gamma; IDA:MGI.
 GO:0050830; P:defense response to Gram-positive bacterium; IDA:MGI.
 GO:0042832; P:defense response to protozoan; IDA:MGI.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR003191; Guanylate-bd_C.
 IPR015894; Guanylate-bd_N.
 IPR027417; P-loop_NTPase. 
Pfam
 PF02263; GBP
 PF02841; GBP_C 
SMART
  
PROSITE
  
PRINTS